Download PDF The Malaria Genome Projects Promise Progress and Prospects
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Book Details :
Published on: 2012-09-07
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Original language: English
The year 2012 marks the tenth anniversary of the announcement of the genome sequence of the human malaria parasite Plasmodium falciparum and that of its mosquito vector Anopheles. The genome sequences were a result of the Plasmodium falciparum Genome Project. This book covers in detail the biology of malaria parasites and the mosquitoes that transmit the disease, how the Genome Projects came into being, the people who created them, and the cadre of scientists who are attempting to see the promise of the Projects realized. The promise was: a more complete understanding of the genes of the parasite (and its vector) would provide a rational basis for the development of antimalarial drugs and vaccines, allow a better understanding of the regulation of the complex life cycle in the red blood and liver cells of the human, identify the genes the parasite uses to thwart the host immune response and the ways in which the parasite evades cure by drug treatments, as well as leading to more effective measures of control transmission. The hope was that cracking the genetic code of Plasmodium and Anopheles would reveal the biochemical Achilles heel of the parasite and its vector, leading to the development of novel drugs and better methods of control, and by finding the targets of protective immunity could result in the manufacture of effective vaccines. Through a historic approach, this book will allow for those new to the field, or those with insufficient background in the sciences, to have an easier entry point. Even scientists already working in the field may better appreciate how discoveries made in the past can impact the direction of future research. Readership: Biochemists, parasitologists, microbiologists, molecular geneticists, immunologists, hematologists, malariologists and tropical physicians and graduate students. Integrative Biology Conference Biology Conferences ... Sessions/Tracks. Conference Series Ltd invites participants from all over the world to 5 th International Conference on Integrative Biology (Integrative Biology 2017 ... Pest and Vector Control Pest Horeca The causes of pest and vectored disease outbreaks Introduction. As pointed out in Chapter 1 a commonly quoted statistic is that without insect pests in the field ... Newswire September 23 2016. The Primitive Streak Last May two research groups [one of which was the Brivanlou lab] announced a breakthrough: they each grew human embryos ... Singularity Q&A KurzweilAI Originally published in 2005 with the launch of The Singularity Is Near. Questions and Answers. So what is the Singularity? Within a quarter century nonbiological ... Design Synthesis and Evaluation of Bifunctional ... Malaria caused by an apicomplexan parasite of the genus Plasmodium remains one of the worlds greatest health challenges along with tuberculosis and AIDS. Genetically modified organism - Wikipedia A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques (i.e. a genetically engineered ... Lecture to Oxford Farming Conference 3 January 2013 ... 07 Mark Lynas from Oxford Farming Conference on Vimeo. I want to start with some apologies. For the record here and upfront I apologise for having spent several ... Science and technology news New Scientist Breaking science and technology news from around the world. Exclusive stories and expert analysis on space technology health physics life and Earth Conference 2015 Wednesday 4 and Thursday 5 November 2015. Royal Society of Medicine 1 Wimpole Street London W1G 0AE London UK. Our tenth conference brought together internationally ... Literature Review: Insights into Formulating a Protective ... ABSTRACT: Malaria unlike many diseases has evolved as a result of millions of years of interactions at various levels with the mammalian system and hence has found ...
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